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Advancing drug development with function-focused profiling at the single-cell level
In this white paper, we explore how drug discovery, often limited by traditional bulk methods and single-cell sequencing, can be accelerated through a function-focused approach. Conventional methods fail to capture cellular diversity and dynamic interactions. The Lightcast platform addresses these challenges by combining step emulsification, machine learning, and optical electrowetting-on-dielectric (oEWOD) technology for real-time, direct functional analysis of single cells. This approach enables in depth functional insights, early identification of promising candidates, and the elimination of suboptimal targets, driving more efficient and cost-effective therapeutic development.